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Chamberlain University Wk 7 Genetics and Genetic Technology Discussion and Reply

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Chamberlain University Wk 7 Genetics and Genetic Technology Discussion and Reply – Description

Required Resources
Read/review the following resources for this activity:
Textbook: Chapter 17, pages 714-734
Weekly Concepts

Initial Post Instructions
Option 1:

In the news, we often hear examples of how DNA or the transfer of genetic information impacted someone’s life. Examples range from DNA fingerprinting to genetically engineered organisms to an individual with a genetic disease. In each of these scenarios, the structure of nucleic acids and the flow of genetic information through mRNA to protein are involved. Using an example from the news or a scholarly article, describe how the structure of DNA or the transfer of genetic information impacted someone’s life. Be sure to use at least one source and include at least one APA formatted citation.
Option 2:
Genetics is a rapidly evolving area of science. Each year advances in genetics bring exciting new technologies to the market. Areas such as forensics, genealogy, and healthcare have all been affected by new genetic technologies. Choose a genetic technology and report on how this technology is affecting or will effect our lives. Give at least one outside source and cite in APA format.
Follow-Up Post Instructions
Respond to at least one peer or the instructor. Further the dialogue by providing more information and clarification.
Possible follow-up topics:
Choose a specific biomolecule found in your diet. What is the source and purpose of this biomolecule?
Choose one of your peers postings on an application of genetics. What are some of the political, social, economic, or ethical ramifications of this technology?
Designer babies are rapidly becoming possible with advances in technology. Discuss with your peers the possible benefits and downsides of this technology. Support your positions with APA formatted citations.
Writing Requirements
Minimum of 2 posts (1 initial & 1 follow-up)

Minimum of 2 sources cited (assigned readings/online lessons and an outside source)
APA format for in-text citations and list of references
Grading

This activity will be graded using the Discussion Grading Rubric. Please review the following link:
Discussion Guidelines

Course Outcomes
CO 10: Contrast the synthesis, composition, structure and functions of major biological macromolecules and Illustrate the process of flow of genetic information.
REPLY

Option 1
DNA, Deoxyribonucleic acid is made up of units of biological building blocks called nucleotides. It is a hereditary material in humans and almost all other organisms. One example of genetic information that has impacted a person’s life is Trisomy 21 also known as Down Syndrome. Down syndrome (DS) is the most common genomic disorder of intellectual disability and is caused by trisomy of Homo sapiens chromosome 21 (Antonarakis et al., 2020). A condition with a person that has an extra chromosome. Down Syndrome determines the baby’s body form and functions during pregnancy and after birth. Today, DNA has changed the field of genetics. Trisomy 21 is a lifelong disorder that many children suffer from. Some common physical features are a flattened face, short neck, small ears, small hands and feet, poor muscle tone or loose joints, and a shorter height than children and adults (CDC, 2022).
According to the National Human Genome Research Institute, most cases of Down syndrome are not inherited but occur as random events during the formation of reproductive cells (eggs and sperm) (2017). It is an error during cell division that results in an abnormal number of chromosomes, and an extra copy of full or partial chromosome 21. A protein called sorting nexin 27 (SNX27) in the brain is depleted in the brains of people with Down’s syndrome (Chandra et al., 2021). SNX27 is strongly linked to Down’s Syndrome via glutamate receptor dysfunction.
Most of the time, Down Syndrome is not passed from parent to child, but theirs a small percentage that can. There are types of screening and diagnostic tests that can be done to detect Down Syndrome during pregnancy. A screening test can tell a woman and her healthcare provider whether her pregnancy has a lower or higher chance of having Down syndrome (CDC, 2022). Screening tests do not provide an actual diagnosis and Diagnostic tests can only detect whether the baby has Down Syndrome. Down Syndrome is a lifelong condition and with early detection, it can help in the long run.  
Reference
Antonarakis, S. E., Skotko, B. G., Rafii, M. S., Strydom, A., Pape, S. E., Bianchi, D. W., Sherman, S. L., & Reeves, R. H. (2020). Down syndrome (Primer). Nature Reviews: Disease Primers, 6(1) https://doi.org/10.1038/s41572-019-0143-7
Bauer, R. C., Birk, J. P., & Marks, P. (2019). Introduction to chemistry (5TH ed.). McGraw-Hill Education.
Chandra, M., Kendall, A., & Jackson, L. S. (2021). Toward Understanding the Molecular Role of SNX27/Retromer in Human Health and Disease. 9. https://doi.org/10.3389/fcell.2021.642378
?CDC. (2022, November 18). Facts about Down syndrome. Centers for Disease Control and Prevention; U.S. Department of Health & Human Services. https://www.cdc.gov/ncbddd/birthdefects/downsyndro…
?National Human Genome Research Institute. (2017, June 29). About Down Syndrome. Genome.gov. https://www.genome.gov/Genetic-Disorders/Down-Synd…
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